Basicaly, it's a casual variety of “so”, oriented towards consequence : 

> *Something happens*  
> — **So**, does it change anything ?


As [cl-r](https://french.stackexchange.com/a/2959/1514) mentions, there are various ways to express the same thing in French :

![ngram](https://i.sstatic.net/9JxJK.png)

And I'd mention in Québec, “*faque*”, a shortened form of “*ce qui fait que*” is *very* common **in oral speech**.

> *Faque je ne dis plus jamais « du coup », moi, maintenant.*